Email address. Those with a penicillin allergy can sometimes use an alternative medication in the early stages. There are three stages: The infection can lie dormant for up to 30 years before returning as tertiary syphilis. Ocular syphilis is another tertiary effect of untreated syphilis, where bacteria affect the optic nerve in the brain, according to the CDC.
During pregnancy and in the tertiary stages, anyone with an allergy will be desensitized to penicillin to allow for treatment.
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